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Koster A, Caserotti P, Patel KV, Matthews CE, Berrigan D, Van Domelen DR, Brychta RJ, Chen KY, Harris TB. Association of sedentary time with mortality independent of moderate to vigorous physical activity. PLoS One. 2012;7(6):e37696. Epub 2012 Jun 13.

This study followed about 1,900 Americans for about three years during which time 145 people died. The study found that those that were more sedentary had a much higher likelihood of death than those that were more active and that moderate or vigorous exercise did not reduce the risk of death related to low levels of physical activity. I.e. another study that shows that being inactive is bad for you even if you exercise at other times.